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Taking this vitamin daily may help you drop pounds. A study at the University of Minnesota found that people who started a weight-loss program with higher levels of D lost more than those who weren't getting enough of the nutrient. Other research suggested that vitamin D appears to boost the effectiveness of leptin, a hormone that signals the brain that you're full. Because it's difficult to get D from food, Shalamar Sibley, MD, an assistant professor of medicine at the university, says you may need to take a vitamin D3 supplement. Many experts now recommend 1,000 international units every day.