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They're packed with polyphenol antioxidants, Dr. Perricone says. Polyphenols fight free radicals and regulate skin's blood flow, giving it rosiness. One pomegranate or a few glasses of juice daily should do the trick. When applied to skin, the fruits' antioxidants help smooth lines and moisturize, Dr. Bank says. Reduce wrinkles with Grassroots Research Labs Pomegranate Super Anti-Oxidant Cream ($35, kohls.com).