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La Roche-Posay Biomedic Pigment Control ($70, laroche-posay.us)
It takes a chemical exfoliator plus a lightening agent to fade freckles and brown marks. "This contains glycolic acid to slough off the dark, damaged cells, and kojic acid to slow the production of skin-darkening melanin," says Elissa Lunder, MD.
Runners-Up
Neutrogena Tone Correcting Concentrated Serum Night from Ageless Intensives, $21.99, drugstore.com
Grassroots Vitamin C Power Brightening Cream SPF 25, $32.50, kohls.com