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Estee Lauder Advanced Night Repair Synchronized Recovery Complex ($47.50, esteelauder.com)
This nongreasy serum, pumped with skin-repairing enzymes, helps reverse the damage from age accelerators like UV light and pollution. The result: a smoother complexion. "The silky texture is great under night cream," says Elissa Lunder, MD, one of our dermatologist testers.
Runners-Up
Neutrogena Anti-Oxidant Booster Serum from Ageless Restoratives, $19.99, drugstore.com
Kinerase HydraBoost Intensive Treatment, $75, sephora.com